Loss of Reason

Volume Four introduced Diabolus Draco, the ultimate evil. I suppose evil isn't the right word. Draco is a purely destructive entity, but he's not evil. More like chaotic neutral. The Cosmos is inexorably linked to the universe, thus his name. So, he's particularly vulnerable to Draco's power.
Like most of our comics, Brain Fart was never finished. And, boy oh boy, did it end on one heck of a cliffhanger.